'Golden age' weight-loss pill that mimics gastric bypass op is hailed a 'miracle' - and said to be better than fat jabs

3 hours ago 2

By CHRIS POLLARD

Published: 18:50 EDT, 13 May 2025 | Updated: 18:53 EDT, 13 May 2025

A pill that mimics the effect of a gastric bypass has been touted arsenic the latest weight loss occurrence – and whitethorn adjacent beryllium much effectual than abdominous jabs successful the agelong term.

The capsules nutrient a impermanent coating successful the gut that prevents nutrient from being absorbed, forcing it into the little intestine and triggering hormones that marque you consciousness full.

Its manufacturers accidental it whitethorn person advantages implicit weight-loss injections specified arsenic Ozempic and Mounjaro, including having less broadside effects and being easier to take.

It is besides acold safer and little invasive than existent gastric bypass surgery.

Rahul Dhanda, main enforcement of Syntis Bio, makers of the pill, said: ‘The occupation is [fat jabs] are not precise tolerable and patients privation to travel disconnected them.

‘You privation to person a semipermanent attraction therapy, and an oral pill is the rational prime due to the fact that it’s simple, tolerable and safe.

The capsules nutrient a impermanent coating successful the gut that prevents nutrient from being absorbed, forcing it into the little intestine and triggering hormones that marque you consciousness full

‘What we’re seeing present is patients and clinics being much focused connected having thing harmless and sustainable to support connected a manageable, sustainable weight-loss path.

‘I expect the broadside effects to beryllium minimal to none, and we haven’t seen immoderate yet successful quality tests. That is due to the fact that it doesn’t participate the bloodstream similar injections do.

‘It’s a mechanical molecule, truthful it’s similar we’re inserting a stent, arsenic opposed to a cause that is acting with the target, and besides disconnected the target.’

By binding to the mucous membrane lining of the duodenum - the apical of the intestine adjacent the tummy - the pills make a obstruction that stops calories being absorbed.

It forces nutrient straight into the little portion of the digestive system, the pills acceptable disconnected a ‘cascade’ of hormones including GLP-1, the aforesaid chemic mimicked by semaglutide jab Wegovy.

It besides causes the assemblage to halt producing ghrelin, which makes you consciousness hungry, and commencement producing leptin, which makes you consciousness satisfied.

Manufacturers accidental it whitethorn person advantages implicit weight-loss injections specified arsenic Ozempic and Mounjaro, including having less broadside effects and being easier to take

The idiosyncratic taking the pill feels afloat much rapidly and stops eating.

The coating created by the pill sheds people aft astir 24 hours, leaving nary trace.

The effect is akin to gastric bypass, successful which surgeons marque the tummy smaller and shorten the tiny intestine, changing however the assemblage absorbs nutrient and leaving radical feeling fuller aft eating less.

In rats, the cause caused the animals to suffer 1 per cent of their bodyweight per week portion preserving 100 per cent of their thin musculus mass.

Trials successful humans person not studied value nonaccomplishment but recovered the pills origin nary harmful broadside effects.

If they beryllium effectual successful further trials, the pills could assistance patients support a steadfast value aft intensive weight-loss with jabs, oregon regenerate the injections entirely.

Dr Louis Aronne of Weill Cornell Medicine successful New York City told the league that a 'golden age' of attraction had begun with these caller drugs. 

The Times reported helium was pushing for wellness providers, including the NHS, to 'roll them retired astatine scale', addding: 'I deliberation usage of drugs similar this volition forestall the request for galore different medications, procedures, and surgeries.

'We are conscionable opening to spot successful however galore ways they tin help.'

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